TY - JOUR
AU - Lim, Da Jung.
AU - Song, Jeong-Sup.
AU - Park, Mirieom.
AU - Lee, Seungki.
AU - Lee, Sarah.
AU - Son, Youn Kyoung.
AU - Kim, Yangseon.
TI - Investigation of Bioactive Compounds and Antimicrobial Activity of the Ethanol Extracts of Aster spathulifolius Maxim.
T2 - Korean Journal of Environmental Agriculture
PY - 2025
VL - 44
PB - The Korean Society of Environmental Agriculture
SP - 299-308
SN - 1225-3537
AB - Aster spathulifolius Maxim., a traditional medicinal plant from the Asteraceae family, is native to Korea and Japan and has been reported to be effective for treating obesity and cardiovascular diseases. This study aimed to investigate its antimicrobial potential against various pathogens, including Escherichia coli, Salmonella enterica serovar Enteritidis, and Aspergillus fumigatus, as well as to analyze the secondary metabolites present in the plant to identify compounds responsible for its antimicrobial activity. The stems and leaves of the plant were dried and subjected to reflux extraction with 70% aqueous ethanol at 25°C for 24 hours, and this was repeated three times. The extract demonstrated significant antimicrobial activity against the gram-negative bacteria E. coli and S. Enteritidis as well as the fungus A. fumigatus. Secondary metabolite analysis using LC-QTOF/MS identified polyphenol compounds, including chlorogenic acid, isochlorogenic acid C, and rhodiosin, that are known for their antioxidant, antitumor, and antibacterial properties. In particular, quantitative evaluation of the indicators chlorogenic acid and 3,5-dicaffeoylquinic acid revealed that they contained 39.11 mg/g and 51.33 mg/g per dry extract product, respectively. In conclusion, A. spathulifolius Maxim. was determined to be particularly effective as an antimicrobial agent against gram-negative bacteria and fungi.
KW - Antimicrobial activity
KW - Aster spathulifolius Maxim.
KW - Bioactive compounds
KW - Chlorogenic acid
KW - 3
KW - 5-Dicaffeoylquinic acid
DO - 10.5338/KJEA.2025.44.31
UR - https://doi.org/10.5338/KJEA.2025.44.31
ER -

Lim, D. J., Song, J. S., Park, M., Lee, S., Lee, S., Son, Y. K., & Kim, Y. (2025). Investigation of Bioactive Compounds and Antimicrobial Activity of the Ethanol Extracts of Aster spathulifolius Maxim. Korean Journal of Environmental Agriculture, 44, 299-308.

Lim, DJ, Song, JS, Park, M, Lee, S, et al. 2025, “Investigation of Bioactive Compounds and Antimicrobial Activity of the Ethanol Extracts of Aster spathulifolius Maxim.”, Korean Journal of Environmental Agriculture, vol. 44, pp. 299-308. Available from: doi:10.5338/KJEA.2025.44.31

Lim, Da Jung et al. “Investigation of Bioactive Compounds and Antimicrobial Activity of the Ethanol Extracts of Aster spathulifolius Maxim.” Korean Journal of Environmental Agriculture 44 (2025): 299-308.

1. Lim DJ, Song JS, Park M, Lee S, Lee S, Son YK, Kim Y. Investigation of Bioactive Compounds and Antimicrobial Activity of the Ethanol Extracts of Aster spathulifolius Maxim. Korean Journal of Environmental Agriculture [Internet]. 2025;44 299-308. Available from: doi:10.5338/KJEA.2025.44.31.

Lim, Da Jung, Jeong-Sup Song, Mirieom Park, Seungki Lee, Sarah Lee, Youn Kyoung Son and Yangseon Kim. “Investigation of Bioactive Compounds and Antimicrobial Activity of the Ethanol Extracts of Aster spathulifolius Maxim.” Korean Journal of Environmental Agriculture 44 (2025): 299-308. doi: 10.5338/KJEA.2025.44.31.